Restylane Refyne® - For smile lines & marionette lines

Flexible refinement for natural expression. Designed to soften moderate smile lines while allowing natural movement and expression.

Refine Your Lines

Restylane Refyne is a dermal filler designed to smooth and soften lines and wrinkles, such as moderate smile lines and lines around the mouth. Designed with XpresHAn Technology™ for flexible refinement of dynamic areas, Restylane Refyne moves with your expressions for natural-looking results.

Treatment Areas​

Benefits of Treatment

Frequently Asked Questions

What is the Restylane family of products?

The Restylane family of products is a brand of hyaluronic acid (HA) dermal fillers designed for natural-looking results. Each product is a clear gel formulation of HA specifically formulated to act like your body’s own naturally produced HA. Each Restylane product is designed for a specific purpose. The portfolio includes Restylane, Restylane-L, Restylane Lyft, Restylane Silk, Restylane Kysse, Restylane Refyne, Restylane Defyne, Restylane Contour, and Restylane Eyelight. Restylane products are indicated only for patients over the age of 21.

Results from treatment with Restylane Refyne have been shown to last up to 1 year for facial wrinkles and folds, like nasolabial folds and marionette lines.

Common side effects can include swelling, redness, pain, bruising, headache, tenderness, lump formation, itching at the injection site, and impaired hand function. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 to 18 days in the lips.

Restylane products should not be used by people who are pregnant, breastfeeding, or under 22 years of age, have recently used drugs that thin the blood or prevent clotting, have had previous bad allergies, have serious allergies to drugs that have previously required in-hospital treatment, have bleeding disorders, or have a known allergy to lidocaine.

Dermal fillers can be used to soften smile lines like nasolabial folds and other fine lines around the mouth.

Fine lines around the mouth can be smoothed out using hyaluronic acid dermal fillers.

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Soften Smile Lines Without Losing Expression

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Refine Your Lines

Book your Restylane Refyne appointment when you’re ready for subtle, natural smoothing.