PRX Derm Perfexion
Revolutionary Age-Defying Skin Treatment. A no-peel, no-downtime treatment that restores firmness, hydration, and radiance from within.
Reverse the Look of Aging—Without Downtime
Yes, you can reverse the appearance of aging and sun damage while enjoying immediate results with no peeling or social downtime.
PRX Derm Perfexion (formerly PRX-T33) is a groundbreaking biorevitalization treatment that improves skin quality from the inside out—without needles, injections, or traditional chemical peeling. It delivers visible rejuvenation while allowing you to return to daily life immediately.
Bio-Revitalizing Skin Beautifying Liquid
PRX Derm Perfexion Skin Beautifying Liquid is applied using a specialized massage technique that allows deep stimulation without damaging the skin’s surface.
The patented formula combines hydrogen peroxide (H₂O₂) with a high concentration of TCA to activate collagen production while preserving the epidermis.
Key advantages include:
- Painless application
- No impact on social activities
- Non-photosensitizing (safe year-round)
- Quick 10–15 minute sessions
- Immediate firming and hydration
What PRX Derm Perfexion Can Improve
PRX Derm Perfexion delivers immediate and cumulative improvements in a wide range of skin concerns
- Sun damage
- Fine lines and wrinkles
- Enlarged pores
- Aging or thinning skin
- Uneven tone and discoloration
- Pitted scars
- Dehydrated skin
- Hyperpigmentation
- Skin laxity and tightening
- Crepey skin
- Stretch marks
- Dullness and redness
Why PRX Is Different
PRX Derm Perfexion is not a peel. There is no frosting, peeling, or visible exfoliation.
Instead, it works at the level of the papillary dermis to stimulate collagen production and skin regeneration—delivering results that are immediate and long-lasting without recovery time.
Made in Italy. Proven Worldwide.
WiQo represents the Italian fusion of science and beauty, developing innovative cosmetic solutions that promote natural skin regeneration gently and progressively.
With over two million applications worldwide, PRX Derm Perfexion has been widely adopted by dermatologists and aesthetic physicians for both face and body rejuvenation.
Real Results. Real People.
After six sessions of PRX Derm Perfexion Skin Beautifying Liquid application and WiQo active skin program.
After six sessions of PRX Derm Perfexion Skin Beautifying Liquid application and WiQo active skin program.
Frequently Asked Questions
What is PRX Derm Perfexion Skin Beautifying Liquid? Is it a peel?
PRX Derm Perfexion Skin Beautifying Liquid is an innovative patented aesthetic product used for specific indications and is FDA conformed in the United States.
It is not a peel since there is no “peeling” or frosting after application. Patented combination of ingredients helps to stimulate collagen formation and promote skin beautification.
Why is PRX Derm Perfexion Skin Beautifying Liquid different than a peel?
PRX Derm Perfexion Skin Beautifying Liquid application protocol does not cause peeling but uses a patented combination of its components to help to stimulate collagen production at the level of the papillary dermis. There is no downtime associated with a standard “chemical peel” and results are immediate and, after completion of the recommended protocol, long-lasting.
What are the benefits of this product?
PRX Derm Perfexion Skin Beautifying Liquid has multiple advantages: it works very well on its own to beautify or refresh the skin of the face, neck, décolleté and body, or it can be combined with any procedures to enhance them. The most common application is on the face, but it can be used to improve stretch marks and recent depressed scars on the face or body.
Can I have PRX Derm Perfexion Skin Beautifying Liquid done if I have active acne?
PRX Derm Perfexion Skin Beautifying Liquid is not contraindicated in acne patients, however, the product should be used with caution and a consultation with your aesthetic physician/dermatologist is recommended. Topical retinoic acid (isotretinoin) should be suspended for 15 days prior to application and resumed once the post-application erythema improved.
Do you have any pre-treatment suggestions?
As a rule it’s not necessary to discontinue the use of cosmetics containing active ingredients (such as AHAs) if the user is tolerating them well. Use of any product causing erythema must be discontinued at least 15 days prior the application of PRX Derm Perfexion Skin Beautifying Liquid and can be resumed at the end of the cycle.
Sunburn alert: products containing AHAs, Retinol or Isotretinoin may increase your skin’s sensitivity to the sun and particularly the possibility of sunburns. The combination of AHA or Retinol products with PRX Derm Perfexion Skin Beautifying Liquid application may increase the skin sensitivity even further. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.
Pay special attention to retinoid-based products, distinguishing between Retinol (vit. A) and Retinoic acid (see table below)
All applications must be performed under the practitioner’s responsibility and referring to PRX Derm Perfexion Skin Beautifying Liquid and WiQo products’ directions for use, and the directions for use of all other products to be combined.
| ACTIVE INGREDIENT | MODE OF ADMINISTRATION | COMPATIBILITY WITH PRX-T33 |
| RETINOL | TOPICAL | Yes if the product is well tolerated |
| TABLETS | Yes | |
| Retinoic Acid (e.g. Isotreinoin) | TOPICAL | Not if the person has been using Retinoic acid in the 15 days before PRX-T33 application. |
| TABLETS | Not if the person has been using Retinoic acid in the 15 days before PRX-T33 application. |
What is the process like during application?
The session will begin with deep delicate cleansing. Then the doctor will test the product on a limited area and proceed to apply PRX Derm Perfexion Skin Beautifying Liquid on the whole area selected for application with a massage, without using needles or injections. You may feel a slight burning or itching sensation, which is normal and shows that the product is working. Keep reporting your sensations to the doctor. If you feel too uncomfortable to continue the application say so and the doctor will suspend the session if necessary. After the doctor has applied the correct number of layers for your indication, they will wash off the residue from your skin with water and apply a post-application cream. Before you leave the practice your doctor will instruct you on the home care dermo-cosmetic regimen.
Is there any discomfort during the application?
Frequently patients ask about discomfort, however PRX Derm Perfexion Skin Beautifying Liquid is well tolerated by most patients. Only minimal itching or burning sensation during application is reported and is considered normal. Please communicate with your aesthetic provider if this sensation increases during procedure and procedure becomes uncomfortable. At this point, will recommend discontinuation of application, neutralization with water, and application of WiQo Moisturizing Face Cream for Dry Skin.
How many applications do I need to see a difference in my skin?
One session is usually sufficient to achieve a temporary effect of skin beautification, however for a long-lasting reversal of signs of aging, your aesthetic provider may recommend 4-6 weekly applications.
How long do I have to wait in between sessions?
In our experience one-week interval is sufficient for repeated applications, but a specific protocol can be recommended by your aesthetic provider based on your individual needs.
Can I combine PRX Derm Perfexion Skin Beautifying Liquid with other procedures?
Our company has developed multiple combination protocols for advanced level providers. Please address your specific needs with your aesthetic provider to determine which protocol is best for you.
If I am doing this before an event, how many days prior should I schedule the appointment?
Everyone’s skin responds differently and if you had PRX Derm Perfexion Skin Beautifying Liquid application, please make decision-based on your previous experience.
For new clients, allow up to 5 days for your skin to resolve any flaking/redness that may occur.
What should I expect immediately post-application?
After the application, your skin will look brighter, plumper, tighter, more rested. There could be some flaking (it means that your skin needed to shed some excess dead cells), moderate redness. Both the flaking and the redness are alleviated by WiQo Moisturizing Face Cream for Dry Skin. Please note that after application with PRX Derm Perfexion Skin Beautifying Liquid your skin may become sensitized to cosmetics. Stick to the WiQo home care program prescribed by your doctor to avoid any side effects.
What is the after care?
Immediately after and in the days following the application you will apply WiQo Moisturizing Face Cream for Dry Skin to restore the hydrolipidic film. From the day following the application, you will apply WiQo Facial Smoothing Fluid for all skin types in the evening, at least half an hour before any other products. If you perform PRX Derm Perfexion Skin Beautifying Liquid on your body from the day following the application you will apply WiQo Smoothing Moisturizing Body Cream for all skin types in the evening.
Am I able to work out/ wear makeup/ be in the sun after application?
Yes, but avoid saunas/steam baths for a few days. Yes, you’ll be able to wear makeup immediately after the session. Yes, you can go in the sun provided you wear a high-level SPF filter suitable to your skin type. Be aware that PRX Derm Perfexion Skin Beautifying Liquid may thin your epidermis, making it tan quicker but also more prone to sunburn. PRX Derm Perfexion Skin Beautifying Liquid is non-photo sensitizing.
Is there any downtime after the application?
You’ll be able to resume your social and professional life immediately after the session. Any redness/light flaking can be addressed with the application of WiQo Moisturizing Face Cream for Dry Skin.
